Ubuyobozi bushinzwe ibiryo n'ibiyobyabwenge（FDA）irimo gusaba amabwiriza y’ibigo by’imbere mu gihugu n’amahanga asabwa kwiyandikisha hakurikijwe itegeko ry’ibiribwa, ibiyobyabwenge, n’amavuta yo kwisiga（itegeko rya FD&C）gushiraho ibisabwa mubikorwa byiza byo gukora mubikorwae mu gukora, gutunganya, gupakira, no gufata ibiryo by'amatungo.FDA iratanga kandi amabwiriza asaba ko ibigo bimwe na bimwe bishyiraho kandi bigashyira mu bikorwa isesengura ry’ibyago no kugenzura ingaruka ziterwa no gukumira ibiryo ku nyamaswa.FDA ifata iki gikorwa kugirango itange ibyiringiro byinshi byuko ibiryo byinyamanswa bifite umutekano kandi ko bitazatera uburwayi cyangwa ibikomere ku nyamaswa cyangwa abantu kandi bigamije kubaka gahunda y’umutekano w’ibiribwa by’amatungo ejo hazaza bituma igezweho, siyanse ndetse n’ingaruka zishingiye ku gukumira bigenzura bisanzwe mubice byose bya sisitemu y'ibiryo by'amatungo.